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>   首页   >   产品   >   一抗   >   精选抗体   >   斑马鱼抗体   >   Zebrafish SIM1 Antibody (N-term)   

Zebrafish SIM1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Zebrafish SIM1 Antibody (N-term) AZb12960a
    Zebrafish SIM1 Antibody (N-term) (Cat. #AP12960a) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the SIM1 antibody detected the SIM1 protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession F1QMF7
Other Accession P05709, Q61045, P81133
Reactivity Zebrafish
Predicted Human, Mouse, Drosophila
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Clone Names RB32160
Calculated MW 82919 Da
Additional info
Other Names Single-minded homolog 1;SIM1;BHLHE14;sim1a;Single-minded homolog 1-A
Target/Specificity This Zebrafish SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Zebrafish SIM1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZebrafish SIM1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name F1QMF7
Research Areas

BACKGROUND

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.

REFERENCES

Ghoussaini, M., et al. Obesity (Silver Spring) 18(8):1670-1675(2010) Tolson, K.P., et al. J. Neurosci. 30(10):3803-3812(2010) Traurig, M., et al. Diabetes 58(7):1682-1689(2009) Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) : Hung, C.C., et al. Int J Obes (Lond) 31(3):429-434(2007)

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