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MS4A1/CD20 Antibody (C-term)

Mouse Monoclonal Antibody (Mab)

     
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  • 1 - MS4A1/CD20 Antibody (C-term) AW5685
    All lanes : Anti-MS4A1/CD20 Antibody (C-term) at 1:3000 dilution Lane 1: Ramos whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: Daudi whole cell lysate Lane 4: Hela whole cell lysate Lane 5: Raji whole cell lysate Lane 6: Rat spleen cell lysate Lane 7: Mouse spleen cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P11836
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 407CT20.1.2
Calculated MW 33kd KDa
Additional info
Gene ID 931
Other Names B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20
Target/Specificity This MS4A1/CD20 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 266-294 amino acids from the C-terminal region of human MS4A1/CD20.
Dilution WB~~1:3000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMS4A1/CD20 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MS4A1
Synonyms CD20
Function This protein may be involved in the regulation of B-cell activation and proliferation.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor
Tissue Location Expressed on B-cells.

BACKGROUND

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

REFERENCES

Weber, M.S., et al. Ann. Neurol. 68(3):369-383(2010)
Wu, D., et al. Am. J. Clin. Pathol. 134(2):258-265(2010)
de Haij, S., et al. Cancer Res. 70(8):3209-3217(2010)
Beers, S.A., et al. Semin. Hematol. 47(2):107-114(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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