|Other Accession||Q2YDE4, Q9QUM9, P60901|
|Reactivity||Human, Mouse, Rat|
|Predicted||Human, Dog, Chicken|
|Calculated MW||H=27,25;M=25;R=27 KDa|
|Other Names||Proteasome subunit alpha type-6, 27 kDa prosomal protein, PROS-27, p27K, Macropain iota chain, Multicatalytic endopeptidase complex iota chain, Proteasome iota chain, PSMA6, PROS27|
|Target/Specificity||This PSMA6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from human PSMA6.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PSMA6 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Colocalizes with TRIM5 in the cytoplasmic bodies.|
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Bey F.,et al.Mol. Gen. Genet. 237:193-205(1993).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.