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FEZ2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - FEZ2 Antibody (N-term) AW5585
    All lanes : Anti-FEZ2 Antibody (N-term) at 1:1000 dilution Lane 1: NCI-H460 whole cell lysate Lane 2: human skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9UHY8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=40,43;R=42,39 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 9637
Antigen Region 1-30
Other Names Fasciculation and elongation protein zeta-2, Zygin II, Zygin-2, FEZ2
Dilution WB~~1:1000
Target/Specificity This FEZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FEZ2.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFEZ2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FEZ2
Function Involved in axonal outgrowth and fasciculation.
Tissue Location Expressed in nonneural tissues, such as heart, lung, spleen, muscle, testis, placenta and melanocytes
Research Areas

BACKGROUND

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin.

REFERENCES

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Assmann, E.M., et al. J. Biol. Chem. 281(15):9869-9881(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Fujita, T., et al. Biochem. Biophys. Res. Commun. 313(3):738-744(2004)

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