|Calculated MW||H=45;M=47,45;R=45 KDa|
|Other Names||Serine protease hepsin, Transmembrane protease serine 1, Serine protease hepsin non-catalytic chain, Serine protease hepsin catalytic chain, HPN, TMPRSS1|
|Target/Specificity||This HPN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 153-188 amino acids from the Central region of human HPN.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HPN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Present in most tissues, with the highest level in liver|
Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2.
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