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SOX10 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - SOX10 Antibody (Center) AW5567
    All lanes : Anti-SOX10 Antibody (Center) at 1:2000 dilution Lane 1: A375 whole cell lysate Lane 2: C6 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P56693
Other Accession Q04888, A5A763, O55170
Reactivity Human, Rat
Predicted Dog, Sheep, Chicken
Host Rabbit
Clonality Polyclonal
Calculated MW H=50,31;M=50;R=50 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 6663
Antigen Region 231-259
Other Names Transcription factor SOX-10, SOX10
Dilution WB~~1:2000
Target/Specificity This SOX10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-259 amino acids from the Central region of human SOX10.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOX10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX10
Function Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087).
Cellular Location Cytoplasm. Nucleus. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250|UniProtKB:Q04888}
Tissue Location Expressed in fetal brain and in adult brain, heart, small intestine and colon
Research Areas
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