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P2RX5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - P2RX5 Antibody (C-term) AW5538
    All lanes : Anti-P2RX5 Antibody (C-term) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 14 - P2RX5 Antibody (C-term) AW5538
    P2RX5 Antibody (C-term) (AW5538)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of P2RX5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, WB
Primary Accession Q93086
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=47,48,44 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 5026
Antigen Region 325-353
Other Names P2X purinoceptor 5, P2X5, ATP receptor, Purinergic receptor, P2RX5, P2X5
Dilution WB~~1:1000
IHC-P~~1:10~50
Target/Specificity This P2RX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-353 amino acids from the C-terminal region of human P2RX5.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsP2RX5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name P2RX5
Synonyms P2X5
Function Receptor for ATP that acts as a ligand-gated ion channel.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed at high levels in brain and immune system
Research Areas

BACKGROUND

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Three transcript variants encoding distinct isoforms have been identified for this gene.

REFERENCES

Kotnis, S., et al. Mol. Pharmacol. 77(6):953-960(2010)
Overes, I.M., et al. Cancer Immunol. Immunother. 58(3):429-439(2009)
Dubyak, G.R. Mol. Pharmacol. 72(6):1402-1405(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Duckwitz, W., et al. J. Biol. Chem. 281(51):39561-39572(2006)

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