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FDFT1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - FDFT1 Antibody (C-term) AW5537
    All lanes : Anti-FDFT1 Antibody (C-term) at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P37268
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=48,41,38,35,43;M=48 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 2222
Antigen Region 332-361
Other Names Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1
Dilution WB~~1:1000
Target/Specificity This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFDFT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FDFT1
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas

BACKGROUND

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

REFERENCES

Chalasani, N., et al. Gastroenterology 139(5):1567-1576(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kovanen, L., et al. Alcohol Alcohol. 45(4):303-311(2010)
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Sjoholm, L.K., et al. J Circadian Rhythms 8, 1 (2010) :

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