|Application ||IHC-P, WB|
|Calculated MW||H=144 KDa|
|Other Names||Insulin receptor-related protein, IRR, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, INSRR, IRR|
|Target/Specificity||This INSRR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 668-702 amino acids from the Central region of human INSRR.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||INSRR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
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