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IL13RA1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - IL13RA1 Antibody (C-term) AW5366
    All lanes : Anti-IL13RA1 Antibody (C-term) at 1/1000 dilution Lane 1: K562 whole cell lysates Lane 2: Raji whole cell lysates Lane 3: HT-29 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P78552
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=49 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 3597
Antigen Region 13-42
Other Names Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19, CD213a1, IL13RA1, IL13R, IL13RA
Dilution WB~~1:1000
Target/Specificity This IL13RA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 207-238 amino acids from the C-terminal region of human IL13RA1.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL13RA1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL13RA1
Synonyms IL13R, IL13RA
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells
Research Areas

BACKGROUND

Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

REFERENCES

Miloux B.,et al.FEBS Lett. 401:163-166(1997).
Gauchat J.-F.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Aman M.J.,et al.J. Biol. Chem. 271:29265-29270(1996).
Wada M.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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