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TYK2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - TYK2 Antibody (C-term) AW5349
    Western blot analysis of lysates from Hela cell line,mouse liver tissue lysate(from left to right), using TYK2 Antibody (C-term)(Cat. #AW5349). AW5349 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
  • 14 - TYK2 Antibody (C-term) AW5349
    Immunohistochemical analysis of paraffin-embedded H. liver section using TYK2 Antibody (C-term)(Cat#AW5349). AW5349 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, WB
Primary Accession P29597
Other Accession Q9R117
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW H=134;M=133 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 7297
Antigen Region 887-922
Other Names Non-receptor tyrosine-protein kinase TYK2, TYK2
Dilution WB~~1:1000
IHC-P~~1:25
Target/Specificity This TYK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 887-922 amino acids from the C-terminal region of human TYK2.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTYK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TYK2
Function Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
Tissue Location Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines
Research Areas

BACKGROUND

Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.

REFERENCES

Firmbach-Kraft I.,et al.Oncogene 5:1329-1336(1990).
Velazquez L.,et al.Cell 70:313-322(1992).
Krolewski J.J.,et al.Oncogene 5:277-282(1990).
Partanen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8913-8917(1990).
Colamonici O.,et al.Mol. Cell. Biol. 14:8133-8142(1994).

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