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ATAD3A Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - ATAD3A Antibody (N-term) AW5324
    Western blot analysis of lysates from NCI-H292,A549 cell line (from left to right), using ATAD3A Antibody (N-term)(Cat. #AW5324). AW5324 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9NVI7
Other Accession Q5T9A4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=71,62 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 55210
Antigen Region 24-48
Other Names ATAD3A;ATPase family AAA domain-containing protein 3A
Dilution WB~~1:1000
Target/Specificity This ATAD3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-48 amino acids from the N-terminal region of human ATAD3A.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATAD3A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATAD3A
Function Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis.
Cellular Location Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N- terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids
Tissue Location Overexpressed in lung adenocarcinomas (at protein level).
Research Areas

REFERENCES

Ota T., et al. Nat. Genet. 36:40-45(2004).
Gregory S.G., et al. Nature 441:315-321(2006).
Bienvenut W.V., et al. Submitted (JUL-2007) to UniProtKB.
Daub H., et al. Mol. Cell 31:438-448(2008).
Choudhary C., et al. Science 325:834-840(2009).

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