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GATA6 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - GATA6 Antibody (C-term) AW5321
    Western blot analysis of lysates from Hela,MCF-7 cell line (from left to right), using GATA6 Antibody (C-term)(Cat. #AW5321). AW5321 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q92908
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW H=60, 45;M=59, 45;Rat=59 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 2627
Antigen Region 551-585
Other Names Transcription factor GATA-6, GATA-binding factor 6, GATA6
Dilution WB~~1:1000
Target/Specificity This GATA6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 551-585 amino acids from the C-terminal region of human GATA6.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGATA6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA6
Function Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in heart, gut and gut-derived tissues
Research Areas

BACKGROUND

Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation.

REFERENCES

Suzuki E.,et al.Genomics 38:283-290(1996).
Huggon I.C.,et al.Biochim. Biophys. Acta 1353:98-102(1997).
Yoshida T.,et al.FEBS Lett. 414:333-337(1997).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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