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DECR1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - DECR1 Antibody (Center) AW5307
    Western blot analysis of lysates from human liver,mouse liver and rat liver tissue lysate (from left to right), using DECR1 Antibody (Center)(Cat. #AW5307). AW5307 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q16698
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW H=36;M=36;Rat=36 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 1666
Antigen Region 241-274
Other Names 4-dienoyl-CoA reductase, mitochondrial, 4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH], DECR1, DECR
Dilution WB~~1:1000
Target/Specificity This DECR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 241-274 amino acids from the Central region of human DECR1.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDECR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DECR1
Synonyms DECR, SDR18C1
Function Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.
Cellular Location Mitochondrion.
Tissue Location Heart = liver = pancreas > kidney >> skeletal muscle = lung.
Research Areas

BACKGROUND

Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.

REFERENCES

Koivuranta K.T.,et al.Biochem. J. 304:787-792(1994).
Ding J.H.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Helander H.M.,et al.Genomics 46:112-119(1997).
Nusbaum C.,et al.Nature 439:331-335(2006).
Choudhary C.,et al.Science 325:834-840(2009).

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