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Mouse Hoxa1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - Mouse Hoxa1 Antibody (Center) AW5236
    Western blot analysis of lysates from mouse kidney,mouse lung tissue lysate (from left to right), using Hoxa1 Antibody (Center)(Cat. #AW5236). AW5236 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P09022
Other Accession O08656, P49639
Reactivity Mouse
Predicted Human, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW H=37;M=36;Rat=36 KDa
Isotype Rabbit Ig
Antigen Source MOUSE
Additional Information
Antigen Region 191-219
Other Names Hoxa1; Era-1; Hox-1.6; Hoxa-1; Homeobox protein Hox-A1; Early retinoic acid 1; Homeobox protein Hox-1.6; Homeoboxless protein ERA-1-399; Homeotic protein ERA-1-993
Dilution WB~~1:1000
Target/Specificity This Mouse Hoxa1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of mouse Hoxa1.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Hoxa1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hoxa1
Synonyms Era-1, Hox-1.6, Hoxa-1
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments. The homeoboxless ERA-1-399 protein could act as a competitive inhibitor of the ERA-1-993 protein by competing for interaction with regulatory protein(s) while being unable to bind to DNA.
Cellular Location Nucleus.

BACKGROUND

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments. The homeobox domain presumably directs sequence-specific DNA binding. The N-terminal portion of ERA-1-993 may be involved in interactions with one or more other regulatory proteins. Such an interaction could regulate either the DNA-binding activity or the transcriptional regulatory activity of ERA-1-993. The homeoboxless ERA-1-399 protein could act as a competitive inhibitor of the ERA-1-993 protein by competing for interaction with regulatory protein(s) while being unable to bind to DNA.

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