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HLA-G Antibody

Mouse Monoclonal Antibody (Mab)

     
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  • 1 - HLA-G Antibody AW5220
    Western blot analysis of lysates from A549,Ramos,MDA-MB-231 cell line (from left to right), using HLA-G Antibody(Cat. #AW5220). AW5220 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P17693
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 800CT6.4.2
Calculated MW H=38 KDa
Additional info
Gene ID 3135
Other Names HLA-G;HLA-6.0; HLAG; HLA class I histocompatibility antigen, alpha chain G; HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; HLA class I histocompatibility antigen, alpha chain G; MHC class I antigen G
Target/Specificity Purified His-tagged HLA-G protein was used to produced this monoclonal antibody.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHLA-G Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HLA-G
Synonyms HLA-6.0, HLAG
Function Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in trophoblasts.
Research Areas

BACKGROUND

Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.

REFERENCES

Shukla H., et al. Nucleic Acids Res. 18:2189-2189(1990).
Geraghty D.E., et al. Proc. Natl. Acad. Sci. U.S.A. 84:9145-9149(1987).
Ishitani A., et al. Submitted (APR-1992) to the EMBL/GenBank/DDBJ databases.
Hampe A., et al. DNA Seq. 10:263-299(1999).
Shiina S., et al. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.

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