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ESRRG Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - ESRRG Antibody (Center) AW5176
    Western blot analysis of lysates from A549,Hela cell line (from left to right), using ESRRG Antibody (Center)(Cat. #AW5176). AW5176 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P62508
Other Accession P62510, P62509
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW H=51,49,49M=51,49 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 2104
Antigen Region 189-221
Other Names ESRRG; ERR3; ERRG2; KIAA0832; NR3B3; Estrogen-related receptor gamma; ERR gamma-2; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3
Dilution WB~~1:1000
Target/Specificity This ESRRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-221 amino acids from the Central region of human ESRRG.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsESRRG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESRRG
Synonyms ERR3, ERRG2, KIAA0832, NR3B3
Function Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.
Cellular Location Nucleus.
Tissue Location Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
Research Areas

BACKGROUND

ESRRG is an orphan receptor that acts as transcription activator in the absence of bound ligand. This protein binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.

REFERENCES

Chen F., Zhang Q., McDonald T.Gene 228:101-109(1999)
Heard D.J., Norby P.L.Mol. Endocrinol. 14:382-392(2000)
Hong H., Yang L., Stallcup M.R.J. Biol. Chem. 274:22618-22626(1999)

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