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ALDOC Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - ALDOC Antibody (C-term) AW5145
    Western blot analysis of lysates from human brain,rat brain,mouse celebellum tissue lysate (from left to right), using ALDOC Antibody (C-term)(Cat. #AW5145). AW5145 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
  • 14 - ALDOC Antibody (C-term) AW5145
    Formalin-fixed and paraffin-embedded human Brain, Cerebellum tissue reacted with ALDOC antibody (C-term) (Cat.#AW5145), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, WB
Primary Accession P09972
Other Accession P09117, P05063, Q9GKW3
Reactivity Human, Mouse, Rat
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW H=39;M=39;Rat=39 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 230
Antigen Region 300-333
Other Names ALDOC; ALDC; Fructose-bisphosphate aldolase C; Brain-type aldolase
Dilution WB~~1:1000
IHC-P~~1:10~50
Target/Specificity This ALDOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-333 amino acids from the C-terminal region of human ALDOC.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALDOC Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDOC
Synonyms ALDC
Research Areas

BACKGROUND

ALDOC is a member of the fructose-biphosphate aldolase protein family. Expressed specifically in the hippocampus and Purkinje cells of the brain, this protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

REFERENCES

Buono,P.,FEBS Lett. 578 (3), 337-344 (2004)
Buono,P.,Nucleic Acids Res. 16 (10), 4733 (1988)
Rottmann,W.H.,Proc. Natl. Acad. Sci. U.S.A. 56 (4), 1275-1282 (1966)

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