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>   首页   >   产品   >   一抗   >   癌症   >   PLAUR Antibody (C-term)   

PLAUR Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - PLAUR Antibody (C-term) AW5128
    Western blot analysis of lysates from A431 cell line,human brain tissue,Hela,K562,MCF-7 cell line (from left to right), using PLAUR Antibody (C-term)(Cat. #AW5128). AW5128 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded H. brain section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded H. brain section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded H. brain section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded H. kidney section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded H. kidney section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded M. brain section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
  • 14 - PLAUR Antibody (C-term) AW5128
    Immunohistochemical analysis of paraffin-embedded R. brain section using PLAUR Antibody (C-term)(Cat#AW5128). AW5128 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, WB
Primary Accession Q03405
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=37,32 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 5329
Antigen Region 273-305
Other Names Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3, CD87, PLAUR, MO3, UPAR
Dilution WB~~1:1000
IHC-P~~1:25
Target/Specificity This PLAUR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 273-305 amino acids from the C-terminal region of human PLAUR.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPLAUR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLAUR
Synonyms MO3, UPAR
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Cellular Location Cell membrane. Cell projection, invadopodium membrane. Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner Isoform 2: Secreted.
Tissue Location Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain
Research Areas

BACKGROUND

Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.

REFERENCES

Roldan A.L.,et al.EMBO J. 9:467-474(1990).
Min H.Y.,et al.J. Immunol. 148:3636-3642(1992).
Bayraktutan U.,et al.Biochem. Soc. Trans. 21:395-395(1993).
Pyke C.,et al.FEBS Lett. 326:69-74(1993).
Casey J.R.,et al.Blood 84:1151-1156(1994).

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