注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   代谢   >   PMM2 Antibody (C-term)   

PMM2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
标注"皇冠"的产品,是满足高质量标准的产品。
了解更多...
  • 1 - PMM2 Antibody (C-term) AW5041
    Western blot analysis of lysates from MCF-7, HepG2, K562, Hela cell line (from left to right), using PMM2 Antibody (C-term)(Cat. #AW5041). AW5041 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
  • 产品详情
  • 实验流程
  • 背景知识
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O15305
Other Accession Q9Z2M7, Q60HD6, Q3SZJ9, NP_000294.1
Reactivity Human
Predicted Mouse, Rat, Monkey, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW H=28;M=28;Rat=28 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 5373
Antigen Region 198-226
Other Names PMM2; Phosphomannomutase 2
Dilution WB~~ 1:1000
Target/Specificity This PMM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human PMM2.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPMM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PMM2
Function Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Cellular Location Cytoplasm.
Research Areas

BACKGROUND

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq].

REFERENCES

Vega, A.I., et al. Hum. Mutat. 30(5):795-803(2009)
Coman, D., et al. Am. J. Med. Genet. A 146(3):389-392(2008)
Vermeer, S., et al. J. Neurol. 254(10):1356-1358(2007)
Coman, D., et al. J Clin Neurosci 14(7):668-672(2007)
Schollen, E., et al. Mol. Genet. Metab. 90(4):408-413(2007)

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69369083 tech.abgent@wuxiapptec.com.


我要评价