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>   首页   >   产品   >   一抗   >   信号转导   >   RAB32 Antibody (N-term)   

RAB32 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - RAB32 Antibody (N-term) AW5040
    Western blot analysis of lysates from SK-BR-3, HepG2 cell line (from left to right), using RAB32 Antibody (N-term)(Cat. #AW5040). AW5040 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q13637
Other Accession NP_006825.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=25 KDa
Isotype Rabbit Ig
Antigen Source HUMAN
Additional Information
Gene ID 10981
Antigen Region 2-28
Other Names RAB32; Ras-related protein Rab-32
Dilution WB~~1:1000
Target/Specificity This RAB32 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-28 amino acids from the N-terminal region of human RAB32.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAB32 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB32
Function Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Cellular Location Mitochondrion. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side Note=Recruited to phagosomes containing S.aureus or M.tuberculosis
Tissue Location Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung
Research Areas

BACKGROUND

Small GTP-binding proteins of the RAB family, such as RAB32, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).

REFERENCES

Hirota, Y., et al. Cell. Mol. Life Sci. 66(17):2913-2932(2009)
Shibata, D., et al. Int. J. Cancer 119(4):801-806(2006)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Alto, N.M., et al. J. Cell Biol. 158(4):659-668(2002)
Bao, X., et al. Eur. J. Biochem. 269(1):259-271(2002)

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