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RHG19 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - RHG19 Antibody (Center) AP9811c
    Western blot analysis of RHG19 Antibody (Center) (Cat. #AP9811c) in T47D cell line lysates (35ug/lane). RHG19 (arrow) was detected using the purified Pab.
  • 4 - RHG19 Antibody (Center) AP9811c
    RHG19 Antibody (Center) (Cat. #AP9811c) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q14CB8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 84986
Other Names Rho GTPase-activating protein 19, Rho-type GTPase-activating protein 19, ARHGAP19
Target/Specificity This RHG19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the Central region of human RHG19.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRHG19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARHGAP19
Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Cellular Location Nucleus.
Tissue Location Strong expression in fetal heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Weak expression in adult pancreas, spleen, thymus, and ovary
Research Areas

BACKGROUND

Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression.

REFERENCES

Lv, L., et al. DNA Seq. 18(3):184-189(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Jikuya, H., et al. DNA Res. 10(1):49-57(2003)

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