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KLC1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - KLC1 Antibody (Center) AP8637c
    KLC1 Antibody (Center) (Cat. #AP8637c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KLC1 antibody detected the KLC1 protein (arrow).
  • 14 - KLC1 Antibody (Center) AP8637c
    Formalin-fixed and paraffin-embedded human hepatocarcinoma with KLC1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • 14 - KLC1 Antibody (Center) AP8637c
    Formalin-fixed and paraffin-embedded H.brain, H.cerebellum tissue reacted with KLC1 Antibody (Center) (Cat#AP8637c).
  • 4 - KLC1 Antibody (Center) AP8637c
    Flow cytometric analysis of widr cells using KLC1 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, FC, E
Primary Accession Q07866
Other Accession P37285
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 65310 Da
Additional info
Gene ID 3831
Other Names Kinesin light chain 1, KLC 1, KLC1, KLC, KNS2
Target/Specificity This KLC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-415 amino acids from the Central region of human KLC1.
Dilution WB~~1:1000
IHC-P~~1:100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKLC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLC1
Synonyms KLC, KNS2
Function Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Cellular Location Cell projection, growth cone. Cytoplasmic vesicle. Cytoplasm, cytoskeleton
Tissue Location Found in a variety of tissues. Mostly abundant in brain and spine.
Research Areas
Alterations in axonal transport motor proteins in sporadic and experimental Parkinson\'s disease.
Author : Chu Y1, Morfini GA, Langhamer LB, He Y, Brady ST, Kordower JH.
Brain. 2012 Jul;135(Pt 7):2058-73. doi: 10.1093/brain/aws133. Epub 2012 Jun 19.
22719003

BACKGROUND

Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.

REFERENCES

Chernajovsky,Y., et.al., DNA Cell Biol. 15 (11), 965-974 (1996) Gyoeva,F.K., et.al., J. Cell. Sci. 113 (PT 11), 2047-2054 (2000)

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