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|Application ||WB, IHC-P, FC, E|
|Calculated MW||65310 Da|
|Other Names||Kinesin light chain 1, KLC 1, KLC1, KLC, KNS2|
|Target/Specificity||This KLC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-415 amino acids from the Central region of human KLC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.|
|Cellular Location||Cell projection, growth cone. Cytoplasmic vesicle. Cytoplasm, cytoskeleton|
|Tissue Location||Found in a variety of tissues. Mostly abundant in brain and spine.|
Author : Chu Y1, Morfini GA, Langhamer LB, He Y, Brady ST, Kordower JH.
Brain. 2012 Jul;135(Pt 7):2058-73. doi: 10.1093/brain/aws133. Epub 2012 Jun 19.
Provided below are standard protocols that you may find useful for product applications.
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Chernajovsky,Y., et.al., DNA Cell Biol. 15 (11), 965-974 (1996) Gyoeva,F.K., et.al., J. Cell. Sci. 113 (PT 11), 2047-2054 (2000)