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APOA2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - APOA2 Antibody (Center) AP7422c
    Anti-APOA2 Antibody (Center) at 1:1000 dilution + human plasma lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 11 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 14 - APOA2 Antibody (Center) AP7422c
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOA2 antibody (Center) (Cat.#AP7422c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P02652
Other Accession P18656
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 336
Other Names Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2, Proapolipoprotein A-II, ProapoA-II, Truncated apolipoprotein A-II, Apolipoprotein A-II(1-76), APOA2
Target/Specificity This APOA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human APOA2.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAPOA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOA2
Function May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
Cellular Location Secreted.
Tissue Location Plasma; synthesized in the liver and intestine
Research Areas

BACKGROUND

APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.

REFERENCES

Duesing,K., BMC Med. Genet. 10, 13 (2009)
Atta,M., Thromb. Haemost. 100 (3), 391-396 (2008)
Blanco-Vaca,F., J. Lipid Res. 42 (11), 1727-1739 (2001)

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