|Application ||IHC-P, WB, E|
|Other Names||Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2, Proapolipoprotein A-II, ProapoA-II, Truncated apolipoprotein A-II, Apolipoprotein A-II(1-76), APOA2|
|Target/Specificity||This APOA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human APOA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||APOA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.|
|Tissue Location||Plasma; synthesized in the liver and intestine|
Provided below are standard protocols that you may find useful for product applications.
APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
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Atta,M., Thromb. Haemost. 100 (3), 391-396 (2008)
Blanco-Vaca,F., J. Lipid Res. 42 (11), 1727-1739 (2001)