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>   首页   >   产品   >   一抗   >   细胞生物学   >   CTSS Antibody (Center)   

CTSS Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CTSS Antibody (Center) AP7382c
    Western blot analysis of CTSS antibody (Center) (Cat.# AP7382c) in MDA-MB231 cell line lysates (35ug/lane). CTSS (arrow) was detected using the purified Pab.
  • 14 - CTSS Antibody (Center) AP7382c
    CTSS Antibody (Center) (Cat.# AP7382c) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CTSS Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • 4 - CTSS Antibody (Center) AP7382c
    CTSS Antibody (Center) (Cat. #AP7382c) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, FC, E
Primary Accession P25774
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37496 Da
Additional info
Gene ID 1520
Other Names Cathepsin S, CTSS
Target/Specificity This CTSS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human CTSS.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTSS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTSS
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L.
Cellular Location Lysosome.
Research Areas

BACKGROUND

The protein CTSS, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The protein can function as an elastase over a broad pH range in alveolar macrophages.

REFERENCES

Lindahl,C., Cancer Genomics Proteomics 6 (3), 149-159 (2009)
Bunatova,K., Int. J. Biol. Markers 24 (1), 47-51 (2009)

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