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Anti-E-Cadherin Antibody

Mouse Anti Human Monoclonal Antibody

     
  • 1 - Anti-E-Cadherin Antibody AP53448
    Western blot detection of E-Cadherin in T47D,HCT116,MDA-MB-468 and Caco-2 cell lysates using E-Cadherin mouse mAb(dilution 1:2000).Predicted band size:135kDa.Observed band size:135kDa.
  • 1 - Anti-E-Cadherin Antibody AP53448
    Western blot detection of E-Cadherin in Mouse embryos and HCT116 cell lysates using E-Cadherin mouse mAb(dilution 1:1000).Predicted band size:135kDa.Observed band size:135kDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P12830
Other Accession NM_004360
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Purification Affinity purified
Calculated MW 135 KDa
Additional Information
Gene ID 999
Other Names Arc 1; CADH1_HUMAN; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 324; CD324; CD324 antigen; cdh1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion molecule; UVO; Uvomorulin.
Dilution WB~~1:1000
Format Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CDH1
Synonyms CDHE, UVO
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Cellular Location Cell junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma- catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane
Tissue Location Non-neural epithelial tissues.
Research Areas

BACKGROUND

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regul

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