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Anti-FADD Antibody

Mouse Monoclonal Antibody

     
  • 1 - Anti-FADD Antibody AP53393
    Western blot detection of FADD in SW480, Jurkat and Hela cell lysates using FADD mouse mAb(dilution 1:500).Predicted band size:28kDa.Observed band size:28kDa.
  • 5 - Anti-FADD Antibody AP53393
    Immunoprecipitation analysis of Hela cell lysates using FADD mouse mAb.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP
Primary Accession Q13158
Other Accession NM_003824
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Immunogen Recombinant human FADD protein.
Purification Affinity purified
Calculated MW 28 KDa
Additional Information
Gene ID 8772
Other Names FADD;FADD protein;FADD_HUMAN;Fas (TNFRSF6) associated via death domain;Fas associated via death domain;Fas associating death domain containing protein;Fas associating death domain containing protein;Fas associating protein;Fas associating protein with death domain;Fas associating protein with death domain;Fas TNFRSF6 associated via death domain;FAS-associated death domain protein;FAS-associating death domain-containing protein;FasTNFRSF6 associated via death domain;FasTNFRSF6 associated via death domain; GIG 3;GIG3;Growth inhibiting gene 3 protein;Growth-inhibiting gene 3 protein;H sapiens mRNA for mediator of receptor induced toxicity;H sapiens mRNA for mediator of receptor induced toxicity;Mediator of receptor induced toxicity;Mediator of receptor induced toxicity;MGC8528;MGC8528;MORT 1;MORT1;MORT1;Protein FADD.
Dilution WB~~1:500
Format Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name FADD
Synonyms MORT1
Function Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Tissue Location Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes
Research Areas

BACKGROUND

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.Active caspase-8 initiate

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