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MVK Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - MVK Antibody AP53356
    All lanes : Anti-MVK Antibody at 1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 42 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q03426
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 42 KDa
Additional info
Gene ID 4598
Other Names Mevalonate kinase, MK, 2.7.1.36, MVK
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MVK (HGNC:7530)
Function Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis (PubMed:9325256, PubMed:18302342).
Cellular Location Cytoplasm. Peroxisome {ECO:0000250|UniProtKB:P17256}
Research Areas

BACKGROUND

May be a regulatory site in cholesterol biosynthetic pathway.

REFERENCES

Schafer B.L.,et al.J. Biol. Chem. 267:13229-13238(1992).
Graef E.,et al.Oncogene 9:81-87(1994).
Houten S.M.,et al.Eur. J. Hum. Genet. 9:253-259(2001).
Houten S.M.,et al.Eur. J. Hum. Genet. 9:651-651(2001).
Hogenboom S.,et al.J. Cell Sci. 117:631-639(2004).

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