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CNTROB Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CNTROB Antibody AP53335
    Anti-CNTROB Antibody at 1:1000 dilution + human spleen lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 101 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q8N137
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 101 KDa
Additional info
Gene ID 116840
Other Names Centrobin, Centrosomal BRCA2-interacting protein, LYST-interacting protein 8, CNTROB, LIP8
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CNTROB
Synonyms LIP8
Function Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole
Tissue Location Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes
Research Areas

BACKGROUND

Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.

REFERENCES

Zou C.,et al.J. Cell Biol. 171:437-445(2005).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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