|Calculated MW||60 KDa|
|Other Names||Rho guanine nucleotide exchange factor 3, Exchange factor found in platelets and leukemic and neuronal tissues, XPLN, ARHGEF3|
|Format||Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.|
|Tissue Location||Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.|
Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
Thiesen S.,et al.Biochem. Biophys. Res. Commun. 273:364-369(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Guo J.H.,et al.Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.