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RhoG Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - RhoG Antibody AP53317
    All lanes : Anti-RhoG Antibody at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P84095
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 21 KDa
Additional info
Gene ID 391
Other Names Rho-related GTP-binding protein RhoG, RHOG, ARHG
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name RHOG
Synonyms ARHG
Function Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Research Areas

BACKGROUND

Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.

REFERENCES

Vincent S.,et al.Mol. Cell. Biol. 12:3138-3148(1992).
Miki T.,et al.Nature 362:462-465(1993).
Puhl H.L. III,et al.Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
Ellerbroek S.M.,et al.Mol. Biol. Cell 15:3309-3319(2004).
Patel J.C.,et al.J. Cell Biol. 175:453-463(2006).

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