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CD248 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CD248 Antibody AP53290
    All lanes : Anti-CD248 Antibody at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 81 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9HCU0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 81 KDa
Additional info
Gene ID 57124
Other Names Endosialin, Tumor endothelial marker 1, CD248, CD248, CD164L1, TEM1
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CD248
Synonyms CD164L1, TEM1
Function May play a role in tumor angiogenesis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts
Research Areas

BACKGROUND

May play a role in tumor angiogenesis.

REFERENCES

St Croix B.,et al.Science 289:1197-1202(2000).
Christian S.,et al.J. Biol. Chem. 276:7408-7414(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Rettig W.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:10832-10836(1992).
Dolznig H.,et al.Cancer Immun. 5:10-10(2005).

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