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TBL1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - TBL1 Antibody AP53272
    Western blot detection of TBL1X in SW480 cell lysates using TBL1X mouse mAb (1:1000 diluted).Predicted band size:58KDa.Observed band size:58KDa.
  • 8 - TBL1 Antibody AP53272
    Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-TBL1X mouse mAb (dilution 1:100).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ICC
Primary Accession O60907
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Calculated MW 58 KDa
Additional Information
Gene ID 6907
Other Names EBI;F box like/WD repeat protein TBL1X;F-box-like/WD repeat-containing protein TBL1X; SMAP 55;SMAP55;TBL 1;TBL 1X;TBL1;TBL1X; TBL1X_HUMAN;Transducin (beta) like 1;Transducin (beta) like 1 X linked;Transducin (beta) like 1X linked;Transducin beta like 1 X linked; Transducin beta like 1X;Transducin beta like 1X protein;Transducin beta like protein 1, X linked;Transducin beta-like protein 1X;Transducin-beta-like protein 1;X-linked.
Dilution WB~~1:1000
ICC~~1:100
Format Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name TBL1X
Synonyms TBL1
Function F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
Cellular Location Nucleus.
Tissue Location Ubiquitous..
Research Areas

BACKGROUND

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

REFERENCES

Bassi M.T.,et al.Am. J. Hum. Genet. 64:1604-1616(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Guenther M.G.,et al.Genes Dev. 14:1048-1057(2000).
Li J.,et al.EMBO J. 19:4342-4350(2000).

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