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GADD45α Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - GADD45α Antibody AP52842
    Western blot detection of GADD45 α in CHO-K1 cell lysate(B)and CHO-K1 transfected by GADD45 α His fusion protein(A)cell lysate using GADD45 α mouse mAb (1:1000 diluted). Predicted band size:22KDa. Observed band size:22KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P24522
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 22 KDa
Additional Information
Gene ID 1647
Other Names DDIT 1; DDIT-1; DDIT1; DNA damage inducible transcript 1; DNA damage-inducible transcript 1 protein; GA45A_HUMAN; GADD45; GADD45A; Growth arrest and DNA damage inducible 45 alpha; Growth arrest and DNA damage inducible alpha; Growth arrest and DNA damage-inducible protein GADD45 alpha.
Dilution WB~~1:1000
Format Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name GADD45A
Synonyms DDIT1, GADD45
Function In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Cellular Location Nucleus.
Research Areas

BACKGROUND

In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

REFERENCES

Papathanasiou M.A.,et al.Mol. Cell. Biol. 11:1009-1016(1991).
Hollander M.C.,et al.J. Biol. Chem. 268:24385-24393(1993).
Zhang Y.,et al.Nucleic Acids Res. 34:485-495(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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