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Noggin Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - Noggin Antibody AP52792
    Western blot detection of Noggin in CHO-K1 cell lysates over-expressing Noggin-PDGFR transmembrane domain fused protein using Noggin mouse mAb (1:1000 diluted).Predicted band size:26KDa.Observed band size:37KDa.
  • 8 - Noggin Antibody AP52792
    Immunocytochemistry staining of HeLa cells surface-expressing Noggin-PDGFR transmembrane domain fused protein using Noggin mouse mAb (dilution 1:100).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ICC
Primary Accession Q13253
Host Mouse
Clonality Monoclonal
Isotype IgG3
Calculated MW 26 KDa
Additional Information
Gene ID 9241
Other Names NOG;NOGG_HUMAN;Noggin;SYM 1;SYM1;Symphalangism 1 (proximal);Synostoses (multiple) syndrome 1;SYNS 1;SYNS1.
Dilution WB~~1:1000
ICC~~1:100
Format ascites
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name NOG
Function Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
Cellular Location Secreted.
Research Areas

BACKGROUND

Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.

REFERENCES

Valenzuela D.M.,et al.J. Neurosci. 15:6077-6084(1995).
Groppe J.,et al.Nature 420:636-642(2002).
Gong Y.,et al.Nat. Genet. 21:302-304(1999).
Takahashi T.,et al.Clin. Genet. 60:447-451(2001).
Dixon M.E.,et al.Genet. Med. 3:349-353(2001).

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