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IL18 binding protein Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - IL18 binding protein Antibody AP52791
    Western blot detection of IL18 binding protein in CHO-K1 cells transfected by IL18BP-PDGFR fusion protein and K562 cell lysates using IL18 binding protein mouse mAb (1:400-1:1000 diluted).Predicted band size:37KDa.Observed band size:37/40KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O95998
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Calculated MW 37 KDa
Additional Information
Gene ID 10068
Other Names I18BP_HUMAN;IL-18BP;IL18 BP;IL18 BPa;IL18BP;IL18BPa;Interleukin 18 binding protein; Interleukin-18-binding protein;MC51L 53L 54L homolog gene product;Tadekinig alfa; Tadekinig-alfa.
Dilution WB~~1:400
Format ascites
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name IL18BP
Function Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Cellular Location Secreted.
Tissue Location Strongly expressed in heart, lung, placenta and spleen.
Research Areas

BACKGROUND

Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.

REFERENCES

Novick D.,et al.Immunity 10:127-136(1999).
Aizawa Y.,et al.FEBS Lett. 445:338-342(1999).
Xiang Y.,et al.Virology 257:297-302(1999).
Kim S.-H.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:1190-1195(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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