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>   首页   >   产品   >   一抗   >   代谢   >   Anti-NRF1 Monoclonal Antibody   

Anti-NRF1 Monoclonal Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - Anti-NRF1 Monoclonal Antibody AP52779
    Western blot detection of TCF11/NRF1 in Hela,K562,CEM and U2OS cell lysates using TCF11/NRF1 mouse mAb (1:1000 diluted).Predicted band size:67KDa.Observed band size:72KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q16656
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Calculated MW 72 KDa
Additional Information
Gene ID 4899
Other Names alpha pal;alpha palindromic binding protein;Alpha palindromic-binding protein;Alpha-pal; locus control region factor 1;NFE2 related factor 1;NRF-1;Nrf1;NRF1_HUMAN;Nuclear respiratory factor 1;transcription factor 11.
Dilution WB~~1:1000
Format Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide,50% glycerol,0.1%BSA.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name NRF1
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed with strongest expression in skeletal muscle
Research Areas

BACKGROUND

Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

REFERENCES

Virbasius C.A.,et al.Genes Dev. 7:2431-2445(1993).
Efiok B.J.S.,et al.J. Biol. Chem. 269:18921-18930(1994).
Gopalakrishnan L.,et al.J. Biol. Chem. 270:18019-18025(1995).
Yang S.J.,et al.Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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