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Musashi-1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - Musashi-1 Antibody AP52765
    Western blot detection of Musashi-1 in U87MG,C6,IMR32,mouse brain and PC12 cell lysates and using Musashi-1 mouse mAb (1:1000 diluted).Predicted band size: 39KDa.Observed band size:39KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O43347
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Calculated MW 39 KDa
Additional Information
Gene ID 4440
Other Names MSI1;Musashi-1;Msi 1;Msi1;MSI1H_HUMAN;Musashi homolog 1;Musashi-1;Musashi1;RNA binding protein Musashi homolog 1;RNA-binding protein Musashi homolog 1.
Dilution WB~~1:1000
Format Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide, 50% glycerol, 0.1%BSA
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MSI1
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Research Areas

BACKGROUND

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

REFERENCES

Good P.,et al.Genomics 52:382-384(1998).
Scherer S.E.,et al.Nature 440:346-351(2006).
Shu H.-J.,et al.Biochem. Biophys. Res. Commun. 293:150-154(2002).
Okano H.,et al.J. Cell Sci. 115:1355-1359(2002).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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