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>   首页   >   产品   >   一抗   >   代谢   >   TXNRD2 Antibody   

TXNRD2 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - TXNRD2 Antibody AP52761
    Western blot detection of TXNRD2 in A431,U251,U2OS,Lncap and Hela cell lysates and using TXNRD2 mouse mAb (1:1000 diluted).Predicted band size: 56KDa.Observed band size: 56KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9NNW7
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 56 KDa
Additional Information
Gene ID 10587
Other Names mitochondrial;selenoprotein Z;SELZ;Thioredoxin reductase 2;Thioredoxin reductase 2 mitochondrial;thioredoxin reductase 3;thioredoxin reductase beta;Thioredoxin reductase TR3;TR 3;TR;TR beta;TR-beta;TRXR 2;TRXR2;TRXR2_HUMAN;TXNRD 2;Txnrd2.
Dilution WB~~1:1000
Format ascites
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name TXNRD2
Synonyms KIAA1652, TRXR2
Function Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low
Research Areas

BACKGROUND

Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.

REFERENCES

Sun Q.-A.,et al.J. Biol. Chem. 274:24522-24530(1999).
Gasdaska P.Y.,et al.FEBS Lett. 442:105-111(1999).
Miranda-Vizuete A.,et al.Eur. J. Biochem. 261:405-412(1999).
Toji S.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Lescure A.,et al.J. Biol. Chem. 274:38147-38154(1999).

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