注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   精选抗体   >   Beclin 1 Antibody   

Beclin 1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - Beclin 1 Antibody AP52755
    Western blot detection of Beclin 1 in Hela,3T3,C6,COS7,CHO-K1,Rat brain and Jurkat cell lysates using Beclin 1 mouse mAb (1:1000 diluted).Predicted band size:52KDa.Observed band size:55KDa.
  • 产品详情
  • 文献引用 : 2
  • 实验流程
  • 背景知识
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q14457
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 55 KDa
Additional Information
Gene ID 8678
Other Names APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;BECN1;BECN1_HUMAN;Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein;GT197;Protein GT197;VPS 30;VPS30.
Dilution WB~~1:1000
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name BECN1
Synonyms GT197
Function Plays a central role in autophagy (PubMed:23184933). Required for the abcission step in cytokinesis (PubMed:20208530). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity)
Tissue Location Ubiquitous.
Research Areas
Inhibition of CRL-NEDD8 pathway as a new approach to enhance ATRA-induced differentiation of acute promyelocytic leukemia cells.
Author : Liu S1,Wan J1,Kong Y1,Zhang Y1,Wan L1,Zhang Z1.
Int J Med Sci. 2018 Apr 3;15(7):674-681. doi: 10.7150/ijms.23782. eCollection 2018.
29910671
Sphingosine Kinase 1 Protects Renal Tubular epithelial cells from Renal Fibrosis via Induction of Autophagy.
Author : Du C1,Ren Y1,Yao F1,Duan J2,Zhao H3,Du Y1,Xiao X1,Duan H4,Shi Y5.
Int J Biochem Cell Biol. 2017 Jul 18. pii: S1357-2725(17)30175-9. doi: 10.1016/j.biocel.2017.07.011. [Epub ahead of print]
28733250

BACKGROUND

Plays a central role in autophagy (PubMed:23184933). Required for the abcission step in cytokinesis (PubMed:20208530). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.

REFERENCES

Liang X.H.,et al.J. Virol. 72:8586-8596(1998).
Aita V.M.,et al.Genomics 59:59-65(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Rommens J.M.,et al.Genomics 28:530-542(1995).
Itakura E.,et al.Mol. Biol. Cell 19:5360-5372(2008).

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价