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Calumenin Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - Calumenin Antibody AP52754
    Western blot detection of Calumenin in SW480,mouse intestine and A431 cell lysates and using Calumenin mouse mAb (1:1000 diluted).Predicted band size: 37KDa.Observed band size:45KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O43852
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 37 KDa
Additional Information
Gene ID 813
Other Names CALU;CALU_HUMAN;Calumenin 1;Calumenin 2;Calumenin;Crocalbin;crocalbin-like protein; FLJ90608;IEF SSP 9302;multiple EF-hand protein;OTTHUMP00000212712;OTTHUMP00000212713; OTTHUMP00000212714;OTTHUMP00000212715.
Dilution WB~~1:1000
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CALU
Function Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
Cellular Location Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver
Research Areas

BACKGROUND

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).

REFERENCES

Vorum H.,et al.Biochim. Biophys. Acta 1386:121-131(1998).
Yabe D.,et al.Genomics 49:331-333(1998).
Peterson R.E. Jr.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Wang Q.,et al.Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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