注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   其他   >   LRRFIP1 Antibody   

LRRFIP1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - LRRFIP1 Antibody AP52750
    Western blot detection of LRRFIP1 in Raji,C2C12,MCF7 and Jurkat cell lysates using LRRFIP1 mouse mAb (1:1000 diluted).Predicted band size:89KDa.Observed band size:160KDa.
  • 产品详情
  • 实验流程
  • 背景知识
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q32MZ4
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 160 KDa
Additional Information
Gene ID 9208
Other Names FLAP1;FLIIAP 1;GC binding factor 2;GCF2;HUFI1;Leucine rich repeat (in FLII) interacting protein 1;Leucine rich repeat flightless interacting protein 1;LRR FLII interacting protein 1;LRRFIP 1;Lrrfip1;MGC10947;MGC119738;MGC119739;NEDD8 conjugating enzyme;TAR RNA interacting protein;TAR RNA-interacting protein;Transcription factor 9 like;TRIP.
Dilution WB~~1:1000
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name LRRFIP1
Synonyms GCF2, TRIP
Function Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Ubiquitously expressed.
Research Areas

BACKGROUND

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

REFERENCES

Reed A.L.,et al.J. Biol. Chem. 273:21594-21602(1998).
Wilson S.A.,et al.Nucleic Acids Res. 26:3460-3467(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Fong K.S.K.,et al.Genomics 58:146-157(1999).
Khachigian L.M.,et al.Circ. Res. 84:1258-1267(1999).

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价