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NUP98 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - NUP98 Antibody AP52748
    Western blot detection of NUP98 in Hela,Jurkat and MCF7 cell lysates using NUP98 mouse mAb (1:1000 diluted).Predicted band size: 98kDa.Observed band size: 98kDa.
  • 5 - NUP98 Antibody AP52748
    Immunoprecipitation analysis of Hela cell lysates using NUP98 mouse mAb.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP
Primary Accession P52948
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 98 KDa
Additional Information
Gene ID 4928
Other Names 96 kDa nucleoporin;98 kDa nucleoporin;ADAR2;ADIR2;GLFG-repeat containing nucleoporin; Nuclear pore complex protein Nup96;Nuclear pore complex protein Nup98 Nup96;Nucleoporin 98kD;nucleoporin 98kDa;Nucleoporin Nup96;Nucleoporin Nup98;NUP196;NUP96;Nup98;Nup98-Nup96;NUP98_HUMAN.
Dilution WB~~1:1000
IP~~1:500
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name NUP98
Synonyms ADAR2
Function Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup98 and Nup96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC.
Cellular Location Nucleus. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex. Note=Nup96 is localized to the nucleoplasmic side of the nuclear pore complex (NPC), at or near the nucleoplasmic basket Dissociates from the dissasembled NPC structure early during prophase of mitosis. Colocalized with NUP153 and TPR to the nuclear basket of NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection
Research Areas

BACKGROUND

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup98 and Nup96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC.

REFERENCES

Borrow J.,et al.Nat. Genet. 12:159-167(1996).
Arai Y.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Fontoura B.M.A.,et al.J. Cell Biol. 144:1097-1112(1999).
Borrow J.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).

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