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>   首页   >   产品   >   一抗   >   心血管   >   CD54(ICAM-1) Antibody   

CD54(ICAM-1) Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - CD54(ICAM-1) Antibody AP52694
    Western blot detection of CD54(ICAM-1) in Raji and SW480 cell lysates and using CD54(ICAM-1) mouse mAb (1:1000 diluted).Predicted band size: 58KDa.Observed band size: 96KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P05362
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Calculated MW 96 KDa
Additional Information
Gene ID 3383
Other Names Antigen identified by monoclonal;BB2;BB 2;BB2;CD 54;CD_antigen=CD54;CD54;CD54 antigen; Cell surface glycoprotein P3.58;Human rhinovirus receptor;ICAM 1;ICAM-1;ICAM1; ICAM1_HUMAN;Intercellular adhesion molecule 1;intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;Major group rhinovirus receptor;MALA 2;MALA2;MyD 10;MyD10; P3.58;Surface antigen of activated B cells;Surface antigen of activated B cells, BB2.
Dilution WB~~1:1000
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ICAM1
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas

BACKGROUND

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

REFERENCES

Simmons D.,et al.Nature 331:624-627(1988).
Staunton D.E.,et al.Cell 52:925-933(1988).
Tomassini J.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:4907-4911(1989).
Voraberger G.F.,et al.J. Immunol. 147:2777-2786(1991).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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