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GATA6 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - GATA6 Antibody AP52675
    Western blot detection of GATA6 in HelaNE,Hela and 293 cell lysates and using GATA6 mouse mAb (1:200 diluted).Predicted band size: 45KDa.Observed band size: 60KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q92908
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 60 KDa
Additional Information
Gene ID 2627
Other Names Gata binding factor 6;Gata binding protein 6;GATA-binding factor 6;Gata6;GATA6_HUMAN; Transcription factor Gata 6;Transcription factor GATA-6.
Dilution WB~~1:200
Format ascites
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name GATA6
Function Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in heart, gut and gut-derived tissues
Research Areas

BACKGROUND

Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity).

REFERENCES

Suzuki E.,et al.Genomics 38:283-290(1996).
Huggon I.C.,et al.Biochim. Biophys. Acta 1353:98-102(1997).
Yoshida T.,et al.FEBS Lett. 414:333-337(1997).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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