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SMYD1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - SMYD1 Antibody AP52666
    Western blot detection of SMYD1 in rat skeletal muscle lysates and using SMYD1 mouse mAb (1:100 diluted). Predicted band size: 56KDa.Observed band size: 56KDa.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q8NB12
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Calculated MW 56 KDa
Additional Information
Gene ID 150572
Other Names BOP;CD8 beta opposite;CD8b opposite;Histone lysine N methyltransferase SMYD1;KMT3D;SET and MYND domain-containing protein 1;SMYD1;SMYD1_HUMAN;Zinc finger MYND domain containing 18;ZMYND18;ZMYND22;zinc finger, MYND domain containing 18.
Dilution WB~~1:100
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name SMYD1
Function Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expression seems mostly restricted to heart and skeletal muscle.
Research Areas

BACKGROUND

Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.

REFERENCES

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hillier L.W.,et al.Nature 434:724-731(2005).
Li D.,et al.Nucleic Acids Res. 37:7059-7071(2009).

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