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IL8 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - IL8 Antibody AP52661
    Western blot detection of IL8 in CHO-K1 transfected by IL8-PDGFR fusion protein cell lysate using IL8 mouse mAb (1:500(A)-1:1000(B) diluted).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P10145
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Calculated MW 20 KDa
Additional Information
Gene ID 3576
Other Names (Ala-IL-8)77;(Ser-IL-8)72;3 10C;310C;AMCF 1;AMCF1;b ENAP;Bbeta thromboglobulin like protein;Beta thromboglobulin like protein;C-X-C motif chemokine 8;CXC chemokine ligand 8;CXCL 8;CXCL8;Emoctakin;GCP 1;GCP-1;GCP/IL-8 protein I;GCP/IL-8 protein II;GCP/IL-8 protein III;GCP/IL-8 protein IV;GCP/IL-8 protein V;GCP/IL-8 protein VI;GCP1; Granulocyte chemotactic protein 1;IL 8;IL-8;IL-8(1-77);IL-8(9-77);IL8;IL8/NAP1 form I;IL8/NAP1 form II;IL8/NAP1 form III;IL8/NAP1 form IV;IL8/NAP1 form V;IL8/NAP1 form VI;IL8_HUMAN; Inteleukin 8;Interleukin8;K 60;K60;LECT;LUCT; Lymphocyte derived neutrophil activating factor;Lymphocyte-derived neutrophil-activating factor;LYNAP;MDNCF;MDNCF-b;MDNCF-c; MONAP;Monocyte derived neutrophil activating peptide;Monocyte derived neutrophil activating protein; Monocyte derived neutrophil chemotactic factor;Monocyte-derived neutrophil chemotactic factor;Monocyte-derived neutrophil-activating peptide;NAF;NAP 1; NAP-1;NAP1;Neutrophil activating factor;Neutrophil activating peptide 1;Neutrophil activating protein 1;Neutrophil-activating factor;Neutrophil-activating protein 1; Protein 3 10C; Protein 3-10C;SCYB 8;SCYB8;Small inducible cytokine subfamily B member 8; T cell chemotactic factor;T-cell chemotactic factor;TSG 1;TSG1;
Dilution WB~~1:500
Format Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CXCL8
Synonyms IL8
Function IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Cellular Location Secreted.
Research Areas

BACKGROUND

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

REFERENCES

Schmid J.,et al.J. Immunol. 139:250-256(1987).
Matsushima K.,et al.J. Exp. Med. 167:1883-1893(1988).
Mukaida N.,et al.J. Immunol. 143:1366-1371(1989).
Kowalski J.,et al.Mol. Cell. Biol. 9:1946-1957(1989).
Hotta K.,et al.Immunol. Lett. 24:165-169(1990).

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