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>   首页   >   产品   >   一抗   >   精选抗体   >   磷酸化抗体   >   STAT5B (Phospho-Ser731) Antibody   

STAT5B (Phospho-Ser731) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - STAT5B (Phospho-Ser731) Antibody AP52370
    Western blot analysis of extracts from RAW264.7 cells, treated with EGF (200ng/ml, 30mins), using STAT5B (phospho-Ser731) antibody.
  • 2 - STAT5B (Phospho-Ser731) Antibody AP52370
    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT5B (phospho-Ser731) antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession P42229
Other Accession P51692
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 90647 Da
Additional info
Gene ID 6776
Other Names Signal transducer and activator of transcription 5A, STAT5A, STAT5
Dilution WB~~1:1000
IHC~~1:50~100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name STAT5A
Synonyms STAT5
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Cellular Location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation
Research Areas

BACKGROUND

Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

REFERENCES

Hou J.,et al.Immunity 2:321-329(1995).
Lin J.X.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Tan D.,et al.Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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