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>   首页   >   产品   >   一抗   >   癌症   >   Rabbit Anti-WNT2B Polyclonal Antibody   

Rabbit Anti-WNT2B Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Rabbit Anti-WNT2B Polyclonal Antibody AP52308
    Lane 1: rat brain lysates Lane 2: mouse intestine lysates probed with Anti WNT2B AVPR2 Polyclonal Antibody, Unconjugated (AP52308) at 1:200 in 4˚C. Followed by conjugation to secondary antibody at 1:3000 90min in 37˚C. Predicted band 43kD. Observed band size: 43kD.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, IHC-P
Primary Accession Q93097
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 43770 Da
Additional info
Gene ID 7482
Other Names WNT13; Protein Wnt-2b; Protein Wnt-13; WNT2B
Dilution WB~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name WNT2B
Synonyms WNT13
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines
Research Areas

BACKGROUND

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.

REFERENCES

Katoh M.,et al.Oncogene 13:873-876(1996).
Katoh M.,et al.Biochem. Biophys. Res. Commun. 275:209-216(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bergstein I.,et al.Genomics 46:450-458(1997).
Picariello G.,et al.Proteomics 8:3833-3847(2008).

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