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>   首页   >   产品   >   一抗   >   免疫学   >   Rabbit Anti-CD166 Polyclonal Antibody   

Rabbit Anti-CD166 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Rabbit Anti-CD166 Polyclonal Antibody AP52264
    Lane 1: human colon carcinoma lysates Lane 2: rat brain lysates probed with Anti CD166 Polyclonal Antibody, Unconjugated (AP52264) at 1:200 in 4˚C. Followed by conjugation to secondary antibody at 1:3000 90min in 37˚C. Predicted band 64kD. Observed band size: 64kD.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, IHC-P
Primary Accession Q13740
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 65102 Da
Additional info
Gene ID 214
Other Names MEMD; CD166; CD166 antigen; Activated leukocyte cell adhesion molecule; ALCAM
Dilution WB~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name ALCAM
Synonyms MEMD
Function Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines.
Research Areas

BACKGROUND

Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.

REFERENCES

Bowen M.A.,et al.J. Exp. Med. 181:2213-2220(1995).
Ikeda K.,et al.J. Biol. Chem. 279:55315-55323(2004).
Abe Y.,et al.Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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